
Gypenoside LI
CAS No. 94987-10-7
Gypenoside LI ( —— )
产品货号. M32144 CAS No. 94987-10-7
Gypenoside LI possesses non-small cell lung carcinoma A549 cell inhibitory activity.
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥2309 | 有现货 |
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50MG | 获取报价 | 有现货 |
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100MG | 获取报价 | 有现货 |
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生物学信息
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产品名称Gypenoside LI
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Gypenoside LI possesses non-small cell lung carcinoma A549 cell inhibitory activity.
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产品描述Gypenoside LI possesses non-small cell lung carcinoma A549 cell inhibitory activity.
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体外实验Gypenoside LI (0-80 μM) inhibits A549 cells in a dose-dependent manner. Gypenoside LI induces G2/M and arrest apoptosis in A549 cells.Gypenoside LI increases intracellular ROS level. Gypenoside LI suppressed migration of A549 cells.Gypenoside LI could obviously suppress the expression of CDK1 protein rather than CDK2 and CDK4 proteins.Gypenoside LI inhibits cell proliferation and upregulates expression of miR-128-3p in melanoma cells.Gypenoside LI (75 and 29.71 μg/mL) can induce intrinsic apoptosis along with S phase arrest. Gypenoside LI inhibited the colony formation ability of melanoma through inhibition of the Wnt/β-catenin signaling pathway.Gypenoside LI induces PARP cleavage, increased the expression of cleaved caspase-9 and BID death agonist, and downregulates the expression of FLIP (long form) and BCl-2 in the A375 and SK-MEL-28 melanoma cells. Cell Viability Assay Cell Line:A549 cells.Concentration:0-80 μM.Incubation Time:24 h.Result:Displayed the strongest activity with the IC50 values of 21.36 ± 0.78 μM.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number94987-10-7
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分子量801
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分子式C42H72O14
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (124.84 mM)
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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